Naloxone suppresses fluid consumption in tests of choice between sodium chloride solutions and water in male and female water-deprived rats

@article{Cooper1984NaloxoneSF,
  title={Naloxone suppresses fluid consumption in tests of choice between sodium chloride solutions and water in male and female water-deprived rats},
  author={Steven J. Cooper and David B. Gilbert},
  journal={Psychopharmacology},
  year={1984},
  volume={84},
  pages={362-367}
}
The effects of naloxone on fluid consumption by water-deprived rats trained to choose between a saline solution and water in a 15-min drinking test were examined. Rats of each sex were allocated to three groups and given access to 0.125% NaCl, 0.6% NaCl, and 1.7% NaCl, respectively, as the alternative to water. Under control conditions they drank substantially more of the hypotonic salt solutions than water, but drank slightly more water than hypertonic salt solution. Naloxone generally reduced… CONTINUE READING

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