Naloxone-induced contracture of ileum from stressed guinea pigs.

  title={Naloxone-induced contracture of ileum from stressed guinea pigs.},
  author={I J Bodycote and Gregory B. Chesher},
  journal={European journal of pharmacology},
  volume={57 2-3},
The in vitro preparation of guinea-pig ileum taken from animals which had been stressed by swimming for 5 min in water at 20 degrees C responded by a dose-dependent contracture to the narcotic antagonist naloxone. This response was antagonised by atropine (8 X 10(-8) g/ml). Ileum preparation from non-stressed guinea pigs did not respond to naloxone in… CONTINUE READING