Nalmefene for treatment of alcohol dependence

@article{Soyka2010NalmefeneFT,
  title={Nalmefene for treatment of alcohol dependence},
  author={Michael Soyka and Susanne R{\"o}sner},
  journal={Expert Opinion on Investigational Drugs},
  year={2010},
  volume={19},
  pages={1451 - 1459}
}
  • M. Soyka, S. Rösner
  • Published 21 October 2010
  • Medicine, Psychology
  • Expert Opinion on Investigational Drugs
Importance of the field: Alcohol use and dependence are frequent disorders. Despite numerous established psychosocial approaches, relapse to heavy drinking is common in alcohol-dependent patients after detoxification and relapse prevention remains a significant medical challenge. Areas covered in this review: The opioidergic system plays a crucial role in mediating the rewarding effects of alcohol, in part by modulating dopaminergic neurotransmission in mesolimbic brain areas. This review will… 
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