Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor

@article{Wu2018NalmefeneAM,
  title={Nalmefene attenuates malignant potential in colorectal cancer cell via inhibition of opioid receptor},
  author={Qichao Wu and X. Chen and Jiaqiang Wang and Peng-fei Sun and M. Weng and Wankun Chen and Zhirong Sun and M. Zhu and C. Miao},
  journal={Acta Biochimica et Biophysica Sinica},
  year={2018},
  volume={50},
  pages={156–163}
}
Morphine is postulated a risk factor in promoting tumor growth and metastasis during the preoperative period, and high glycolysis of tumor cells is proved to accelerate tumor progression. In this study, we investigated whether nalmefene, an opioid receptor inhibitor, could inhibit CT26 colon cancer cell growth through influencing cell glycolysis. CCK8 and transwell migration assays showed that nalmefene inhibited CT26 cells viability and migration in a concentration-dependent manner… Expand

References

SHOWING 1-10 OF 42 REFERENCES
Morphine promotes cancer stem cell properties, contributing to chemoresistance in breast cancer
Propofol attenuates pancreatic cancer malignant potential via inhibition of NMDA receptor
The Novel Role of the Mu Opioid Receptor in Lung Cancer Progression: A Laboratory Investigation
Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling
c-Myc transactivation of LDH-A: implications for tumor metabolism and growth.
  • H. Shim, C. Dolde, +5 authors C. Dang
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
  • 1997
...
1
2
3
4
5
...