NaOH-catalyzed crossed Claisen condensation between ketene silyl acetals and methyl esters.
We have developed a practical crossed Claisen condensation between ketene silyl acetals and methyl esters using catalytic NaOH to obtain alpha-monoalkylated beta-keto esters and inaccessible alpha,alpha-dialkylated beta-keto esters.
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tris(trimethylsilyl)silyl enol ether
type I interferon receptor
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