NaG: a sodium channel-like mRNA shared by Schwann cells and other neural crest derivatives.

@article{Felts1997NaGAS,
  title={NaG: a sodium channel-like mRNA shared by Schwann cells and other neural crest derivatives.},
  author={Paul A. Felts and J Andrew Black and Sulayman D. Dib-Hajj and Stephen G. Waxman},
  journal={Glia},
  year={1997},
  volume={21 3},
  pages={269-76}
}
NaG, a member of subfamily 2, was originally characterized as a "glial" sodium channel, and is expressed at high levels in Schwann cells in vivo. However, NaG has also been shown by in situ hybridization to be highly expressed in rat dorsal root ganglion (DRG) neurons, which, like Schwann cells, are neural crest derivatives. In the present study, we used non-isotopic in situ hybridization with a riboprobe for NaG, in conjunction with RT-PCR, to determine whether NaG is expressed in tissues… CONTINUE READING