NaCl detection thresholds: comparison of Fischer 344 and Wistar rats.

  title={NaCl detection thresholds: comparison of Fischer 344 and Wistar rats.},
  author={Sharon N D A Clarke and Ming Teng Koh and I. Leonard Bernstein},
  journal={Chemical senses},
  volume={26 3},
Adult Fischer 344 (F344) rats fail to display any preference for NaCl solutions at concentrations typically preferred by other rat strains. To determine whether this behavior is due to a strain difference in NaCl detection threshold, a conditioned taste aversion (CTA) was first established to a suprathreshold concentration of NaCl (0.1 M). Then, a series of dilute NaCl solutions, ranging from 0.0 to 0.011 M NaCl, were presented to F344 (n = 16) and Wistar (n = 16) rats. The lowest concentration… CONTINUE READING
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