Na-K-ATPase in isolated rabbit tubules after unilateral nephrectomy and Na+ loading.

@article{Scherzer1985NaKATPaseII,
  title={Na-K-ATPase in isolated rabbit tubules after unilateral nephrectomy and Na+ loading.},
  author={Pnina Scherzer and H. Wald and J W Czaczkes},
  journal={The American journal of physiology},
  year={1985},
  volume={248 4 Pt 2},
  pages={F565-73}
}
Na-K-ATPase activity was studied in tubule segments from the cortex and medulla of rabbit kidneys under normal conditions, after unilateral nephrectomy, and after chronic salt loading. After unilateral nephrectomy kidney weight increased by 37% and Na-K-ATPase activity rose significantly in all nephron segments by 36-200% (P less than 0.01). Oral salt loading for 2 wk with 0.5% NaCl caused an increase in GFR and in absolute sodium excretion as well as reabsorption; plasma aldosterone decreased… CONTINUE READING

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