Na+-activated K+ current contributes to postexcitatory hyperpolarization in neocortical intrinsically bursting neurons.

@article{Franceschetti2003NaactivatedKC,
  title={Na+-activated K+ current contributes to postexcitatory hyperpolarization in neocortical intrinsically bursting neurons.},
  author={Silvana Franceschetti and Tatiana Lavazza and Giulia Curia and Patrizia Aracri and Ferruccio Panzica and Giulio Sancini and G. Avanzini and Jacopo Magistretti},
  journal={Journal of neurophysiology},
  year={2003},
  volume={89 4},
  pages={2101-11}
}
The ionic mechanisms underlying the termination of action-potential (AP) bursts and postburst afterhyperpolarization (AHP) in intrinsically bursting (IB) neocortical neurons were investigated by performing intracellular recordings in thin slices of rat sensorimotor cortex. The blockade of Ca(2+)-activated K(+) currents enhanced postburst depolarizing afterpotentials, but had inconsistent and minor effects on the amplitude and duration of AHPs. On the contrary, experimental conditions resulting… CONTINUE READING

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