Na+,K+-ATPase was found to be the membrane component responsible for the hydrophobic behavior of the brain membrane tubulin.

@article{Alonso1998NaKATPaseWF,
  title={Na+,K+-ATPase was found to be the membrane component responsible for the hydrophobic behavior of the brain membrane tubulin.},
  author={{\'A}lvaro Alonso and M Nu{\~n}ez-Fernandez and Dante Miguel Beltramo and C{\'e}sar Horacio Casale and H{\'e}ctor S. Barra},
  journal={Biochemical and biophysical research communications},
  year={1998},
  volume={253 3},
  pages={824-7}
}
We have previously described that the tubulin isolated from brain membranes as a hydrophobic compound by partitioning into Triton X-114 is a peripheral membrane protein [corrected]. The hydrophobic behavior of this tubulin is due to its interaction with membrane protein(s) and the interaction occurs principally with the acetylated tubulin isotype. In the present work we identified the membrane protein that interacts with tubulin as the Na+,K+-ATPase alpha subunit by amino acid sequencing. Using… CONTINUE READING
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