Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress.

@article{Lima2008NaKATPaseAI,
  title={Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress.},
  author={Frederico Diniz Lima and Mauren Assis Souza and Ana Fl{\'a}via Furian and Leonardo Magno Rambo and Leandro Rodrigo Ribeiro and Felipe Villa Martignoni and Maur{\'i}cio Scopel Hoffmann and Michele Rechia Fighera and Luiz Fernando Freire Royes and Mauro Schneider Oliveira and Carlos Fernando de Mello},
  journal={Behavioural brain research},
  year={2008},
  volume={193 2},
  pages={306-10}
}
Traumatic brain injury (TBI) is a devastating disease that commonly causes persistent mental disturbances and cognitive deficits. Although studies indicate that oxidative stress and functional deficits occurring after TBI are interrelated events, the knowledge of the mechanisms underlying the development of such cognitive deficits has been limited. Thus, in the present study, we investigated the effect of fluid percussion brain injury (FPI) on a spatial learning task and levels of oxidative… CONTINUE READING
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