Na+,K(+)-ATPase expression in maleic-acid-induced Fanconi syndrome in rats.

@article{Castao1997NaKATPaseEI,
  title={Na+,K(+)-ATPase expression in maleic-acid-induced Fanconi syndrome in rats.},
  author={Esther Casta{\~n}o and P Marzabal and Fco Javier Casado and Antonio Felipe and Marçal Pastor-Anglada},
  journal={Clinical science},
  year={1997},
  volume={92 3},
  pages={247-53}
}
Na+,K(+)-ATPase activity and its alpha 1 subunit protein and mRNA in kidney cortex were monitored in rats developing Fanconi syndrome after the administration of maleate. Na+,K(+)-ATPase activity was significantly lower than in saline-injected controls, although this was partially mediated by a general, non-specific decrease in the cortex protein content. 2. The low activity of the sodium pump correlated with low abundance of alpha 1 subunit mRNA and protein levels. Hsp60 protein levels were… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 24 references

The metabolic bases of inherited disease

  • CR I . Scriver, AL Beaudet, WS Sly, D. Valle
  • 7th edn. New York McGraw-Hill,
  • 1995

Tubular aspects of hereditary and developmental disorders of the kidney

  • KS Roth, S Segal
  • 1995

; 129 1704 . transport by renal membranes from dogs with spontaneous idiopathic Fanconi syndrome

  • Hsu BYL, SL Wehrli, Yandrasitz
  • 1994

lmmunodetection of Na + , K + - ATPase a 3 isoform in renal and nerve tissues

  • EA Arystarkhova, OE Lakhtina, NN Mcdyanov
  • Biochim Biophys Acta
  • 1994

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