NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes.

@article{Bardoni2003NUFIP1F,
  title={NUFIP1 (nuclear FMRP interacting protein 1) is a nucleocytoplasmic shuttling protein associated with active synaptoneurosomes.},
  author={Barbara Bardoni and Rob Willemsen and Ivan Jeanne Weiler and Annette Schenck and Lies-anne Severijnen and Colette Hindelang and Enzo Lalli and Jean-Louis Mandel},
  journal={Experimental cell research},
  year={2003},
  volume={289 1},
  pages={95-107}
}
Fragile X syndrome, the most common cause of inherited mental retardation, is caused by the absence of FMRP (Fragile X Mental Retardation Protein). FMRP is an RNA binding protein reported to be involved in translational control, notably at postsynaptic sites of protein synthesis as a part of a multiprotein/mRNA complex. One of the FMRP interactors, NUFIP1, is an RNA binding protein with an expression profile matching that of FMRP. We now show that in the nucleus NUFIP1 is localized in the… CONTINUE READING
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