NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells.

@article{Schwartz2005NTera2AM,
  title={NTera2: a model system to study dopaminergic differentiation of human embryonic stem cells.},
  author={Catherine Schwartz and Charles E. Spivak and Shawn C. Baker and T. K. McDaniel and Jeanne F Loring and Cuong Nguyen and Francis J. Chrest and Robert P. Wersto and Ernest Arenas and Xianmin Zeng and William J. Freed and Mahendra S. Rao},
  journal={Stem cells and development},
  year={2005},
  volume={14 5},
  pages={
          517-34
        }
}
NTera2, a human embryonal carcinoma (EC) stem cell line, shares many characteristics with human embryonic stem cells (hESCs). To determine whether NTera2 can serve as a useful surrogate for hESCs, we compared global gene expression between undifferentiated NTera2, multiple undifferentiated hESC cell lines, and their differentiated derivatives, and we showed that NTera2 cells share multiple markers with hESCs. Similar to hESCs, NTera2 cells differentiated into TH-positive cells that express… CONTINUE READING

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