• Corpus ID: 23591016

NTP technical report on the toxicity studies of 1,6-Hexanediamine Dihydrochloride (CAS No. 6055-52-3) Administered by Drinking Water and Inhalation to F344/N Rats and B6C3F1 Mice.

@article{Hbert1993NTPTR,
  title={NTP technical report on the toxicity studies of 1,6-Hexanediamine Dihydrochloride (CAS No. 6055-52-3) Administered by Drinking Water and Inhalation to F344/N Rats and B6C3F1 Mice.},
  author={Charles D. H{\'e}bert},
  journal={Toxicity report series},
  year={1993},
  volume={24},
  pages={
          1-D8
        }
}
  • C. Hébert
  • Published 1 March 1993
  • Biology, Medicine
  • Toxicity report series
1,6-Hexanediamine (HDA) is an aliphatic amine that is produced in large volumes in the United States. HDA is widely used as a corrosion inhibitor in lubricants and as an intermediate in the industrial synthesis of paints, resins, inks, and textiles. Toxicity studies of the dihydrochloride salt of HDA (HDDC) were conducted in male and female Fischer 344/N rats and B6C3F1 mice by the drinking water (2-week studies only) and whole-body inhalation routes (2-week and 13-week studies). Animals were… 
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TLDR
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Nine chemicals, with a range from extremely to slightly toxic, were used to measure the oral LD50 in both fasted and non‐fasted rats, and the use of non‐ fasted rats in acute oral toxicity determinations allows both the establishment of relative potency and the estimation of dosage levels for further repeated dose oral studies.
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TLDR
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TLDR
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