NT3 expressed in skin causes enhancement of SA1 sensory neurons that leads to postnatal enhancement of Merkel cells

@article{Krimm2004NT3EI,
  title={NT3 expressed in skin causes enhancement of SA1 sensory neurons that leads to postnatal enhancement of Merkel cells},
  author={Robin F. Krimm and Brian M. Davis and C. Jeffery Woodbury and Kathryn M. Albers},
  journal={Journal of Comparative Neurology},
  year={2004},
  volume={471}
}
To determine the role of NT3 in the postnatal maturation of Merkel cell (MC) sensory neurite complexes (touch domes), we examined the development of their neural and end‐organ components in wild‐type and transgenic mice that overexpress NT3 (NT3‐OE). Touch domes are sensory complexes of the skin that contain specialized MCs innervated by slowly adapting type 1 (SA1) neurons. Touch domes are dependent on NT3 and, though formed in newborn mice that lack NT3, are severely depleted during postnatal… 

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