NSAIDs can have adverse effects on bone healing.

  title={NSAIDs can have adverse effects on bone healing.},
  author={Robert W van Esch and Maurice M Kool and Saskia van As},
  journal={Medical hypotheses},
  volume={81 2},
The science of osteoimmunology, a relatively new field of research, reveals the important interactions between the immune system and skeletal system. Interactions occur between prostaglandin metabolism, inflammatory proteins and bone metabolism. Systemic as well as local sources of inflammation appear to be actively involved in both bone formation and resorption. Non Steroidal Anti-Inflammatory Drugs (NSAIDs) can play a detrimental role in bone fractures, opposing the aim of the intervention… CONTINUE READING


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