NSAIDs and faecal blood loss in elderly patients with osteoarthritis: is plasma half-life relevant?

Abstract

BACKGROUND Nonsteroidal anti-inflammatory drugs (NSAIDs) vary in their degree of gastrointestinal (GI) toxicity. NSAIDs with longer half-lives are of particular concern as they may be more toxic in the elderly. AIM To compare the GI toxicity, by measurement of faecal blood loss, of short, intermediate and long half-life NSAID treatments compared with… (More)

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Cite this paper

@article{Scharf1998NSAIDsAF, title={NSAIDs and faecal blood loss in elderly patients with osteoarthritis: is plasma half-life relevant?}, author={Simon L Scharf and Rafał Kwiatek and Antony Marcello Ugoni and N. Christophidis}, journal={Australian and New Zealand journal of medicine}, year={1998}, volume={28 4}, pages={436-9} }