NSAIDs and Alcohol: Never the Twain Shall Mix?
@article{Pfau1999NSAIDsAA, title={NSAIDs and Alcohol: Never the Twain Shall Mix?}, author={Patrick Pfau and Gary R. Lichtenstein}, journal={American Journal of Gastroenterology}, year={1999}, volume={94}, pages={3098-3101} }
Accurately diagnosing and successfully treating chronic cough due to GERD can be difficult. The diagnosis is not straightforward, and the optimal way to treat all patients with this problem has yet to be determined. We agree with Ourset al. (1) that a therapeutic, empiric trial with a proton pump inhibitor such as omeprazole 40 mg b.i.d. for 2 wk is a reasonableinitial diagnostic approach if the patient fits the clinical profile for GER-induced cough and, for whatever reason, one does not…
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References
SHOWING 1-10 OF 43 REFERENCES
A prospective evaluation of esophageal testing and a double-blind, randomized study of omeprazole in a diagnostic and therapeutic algorithm for chronic cough
- MedicineAmerican Journal of Gastroenterology
- 1999
It is suggested that the best diagnostic and therapeutic approach, after excluding asthma and postnasal drip syndrome, is empiric treatment for 2 wk with a high dose proton pump inhibitor.
Chronic cough due to gastroesophageal reflux. Clinical, diagnostic, and pathogenetic aspects.
- MedicineChest
- 1993
There is a clinical profile that prospectively predicts which patients have chronic cough due to GER and it was determined that the cough was most likely due to stimulation of the distal esophagus, not aspiration.
Gastroduodenal damage due to drugs, alcohol and smoking.
- MedicineClinics in gastroenterology
- 1984
Although for most of the other non-steroidal anti-inflammatory drugs (NSAIDs), anecdotal reports on putative drug-related major gastric bleeding or peptic ulceration exist, the ulcerogenicity of these drugs has not yet been conclusively proven in controlled studies.
Pathogenesis of chronic persistent cough associated with gastroesophageal reflux.
- MedicineAmerican journal of respiratory and critical care medicine
- 1994
In patients with cough and reflux as determined by 24-h ambulatory esophageal pH monitoring, there was a significant increase in cough frequency, median, and amplitude, with HCl infusion, compared with control subjects, but there was no difference in cough duration.
Chronic persistent cough in the adult: the spectrum and frequency of causes and successful outcome of specific therapy.
- MedicineThe American review of respiratory disease
- 1981
Using an anatomic, diagnostic protocol, the cause of chronic persistent cough can be consistently determined and postnasal drip and/or bronchial asthma are very common causes of cough.
The American College of Gastroenterology Bleeding Registry: preliminary findings.
- MedicineThe American journal of gastroenterology
- 1997
Data suggest that ACG members manage sick patients with severe gastrointestinal bleeding who require hospitalization, transfusions, and endoscopic treatment, and these preliminary results will serve as an impetus to conduct further survey studies of gastrointestinal bleeding and other common digestive disease conditions.
Upper gastrointestinal bleeding in relation to previous use of analgesics and non-steroidal anti-inflammatory drugs
- MedicineThe Lancet
- 1991
Gastro-oesophageal reflux related cough and its response to laparoscopic fundoplication
- MedicineThorax
- 1998
Laroscopic Nissen fundoplication is effective in the control of cough in patients with gastro-oesophageal reflux disease, with or without primary respiratory disease.
Epidemiological evidence for the association of aspirin and acute gastrointestinal bleeding.
- MedicineGut
- 1970
No method of study has yet been devised which would allow prospective investigation of the role of aspirin in inducing haemorrhage and therefore retrospective comparisons remain the only available techniques.
The association of nonsteroidal anti-inflammatory drugs with upper gastrointestinal tract bleeding.
- MedicineArchives of internal medicine
- 1987
Non-steroidal anti-inflammatory drugs are associated with UGI bleeding, although the magnitude of the increased risk is reassuringly small, and a linear dose-response relationship and a quadratic duration- response relationship were demonstrated.