NSAID use and progression of chronic kidney disease.

@article{Gooch2007NSAIDUA,
  title={NSAID use and progression of chronic kidney disease.},
  author={Katherine L Gooch and Bruce F. Culleton and Braden J. Manns and Jianguo Zhang and Helman S Alfonso and Marcello Tonelli and C Frank and Scott W. Klarenbach and Brenda R. Hemmelgarn},
  journal={The American journal of medicine},
  year={2007},
  volume={120 3},
  pages={
          280.e1-7
        }
}
PURPOSE The effects of nonselective and selective cyclooxygenase-2 specific (COX-2) nonsteroidal anti-inflammatory drug (NSAID) use on the progression of chronic kidney disease (CKD) is uncertain. Due to the high prevalence of both CKD and NSAID use in older adults, we sought to determine the association between NSAID use and the progression of CKD in an elderly community-based cohort. METHODS All subjects > or =66 years of age who had at least one serum creatinine measurement in 2 time… CONTINUE READING

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