NRP-1 expression in bladder cancer and its implications for tumor progression

  title={NRP-1 expression in bladder cancer and its implications for tumor progression},
  author={Wen Cheng and Dian Fu and Zhi-feng Wei and Feng Xu and Xiaofeng Xu and You-Huang Liu and Jing-ping Ge and Feng Tian and Cong-hui Han and Zheng-yu Zhang and Liming Zhou},
  journal={Tumor Biology},
Neuropilin-1 (NRP-1) overexpression has been reported in a variety of human cancers. However, the role of NRP-1 in bladder cancer (BC) remains unclear. The aim of present study was to analyze NRP-1 protein expression in BC tissues and to assess its prognostic significance for BC. NRP-1 messenger ribonucleic acid (mRNA) and protein expression were determined by real-time quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) and immunohistochemistry in specimens of primary cancer… CONTINUE READING
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