NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade.

@article{Kendall2005NRAGEMP,
  title={NRAGE mediates p38 activation and neural progenitor apoptosis via the bone morphogenetic protein signaling cascade.},
  author={Stephen Edward Kendall and Chiara Battelli and Sarah Irwin and Jane G. Mitchell and Carlotta A. Glackin and Joseph M. Verdi},
  journal={Molecular and cellular biology},
  year={2005},
  volume={25 17},
  pages={7711-24}
}
Understanding the molecular events that govern neural progenitor lineage commitment, mitotic arrest, and differentiation into functional progeny are germane to our understanding of neocortical development. Members of the family of bone morphogenetic proteins (BMPs) play pivotal roles in regulating neural differentiation and apoptosis during neurogenesis through combined actions involving Smad and TAK1 activation. We demonstrate that BMP signaling is required for the induction of apoptosis of… CONTINUE READING

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NRAGE MEDIATES p38 ACTIVATION AND APOPTOSIS 7723 on Jauary 27, 2018 by gest hp://m c.asm .rg/ D ow nladed fom

  • A. H. Salehi, P. P. Roux, +4 authors VOL
  • Neuron
  • 2005
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