NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development.

Abstract

NRH: quinone oxidoreductase 2 (NQO2) is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone to hydroquinones. Herein, we assessed the protein expression, subcellular localization, and possible functions of NQO2 in mouse oocyte meiotic maturation and embryo development. Western blot analysis detected high… (More)
DOI: 10.1093/biolre/iox098

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Cite this paper

@article{Chen2017NQO2IR, title={NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development.}, author={Dandan Chen and Xin Li and Xiaoyun Liu and XiaoYu Liu and Xiuying Jiang and Juan Du and Qian Wang and Yuanjing Liang and W. Y. Ma}, journal={Biology of reproduction}, year={2017}, volume={97 4}, pages={598-611} }