NPAS3 Regulates Transcription and Expression of VGF: Implications for Neurogenesis and Psychiatric Disorders

  title={NPAS3 Regulates Transcription and Expression of VGF: Implications for Neurogenesis and Psychiatric Disorders},
  author={D. Yang and W. Zhang and A. Padhiar and Yao Yue and Yonghui Shi and Tiezheng Zheng and K. Davis and Y. Zhang and M. Huang and Y. Li and Li Sha},
  journal={Frontiers in Molecular Neuroscience},
  • D. Yang, W. Zhang, +8 authors Li Sha
  • Published 2016
  • Biology, Medicine
  • Frontiers in Molecular Neuroscience
  • Neuronal PAS domain protein 3 (NPAS3) and VGF (VGF Nerve Growth Factor (NGF) Inducible) are important for neurogenesis and psychiatric disorders. Previously, we have demonstrated that NPAS3 regulates VGF at the transcriptional level. In this study, VGF (non-acronymic) was found regulated by NPAS3 in neuronal stem cells. However, the underlying mechanism of this regulation remains unclear. The aim of this study was to explore the correlation of NPAS3 and VGF, and their roles in neural cell… CONTINUE READING
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    • Open Access


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