NOX2 activated by α1-adrenoceptors modulates hepatic metabolic routes stimulated by β-adrenoceptors.

@article{DazCruz2011NOX2AB,
  title={NOX2 activated by α1-adrenoceptors modulates hepatic metabolic routes stimulated by β-adrenoceptors.},
  author={Antonio D{\'i}az-Cruz and Mar{\'i}a Magdalena Vilchis-Landeros and Raquel Guinzberg and Rafael Villalobos-Molina and Enrique Pi{\~n}a},
  journal={Free radical research},
  year={2011},
  volume={45 11-12},
  pages={1366-78}
}
The NADPH oxidase (NOX) family of enzymes oxidase catalyzes the transport of electrons from NADPH to molecular oxygen and generates O(2)(•-), which is rapidly converted into H(2)O(2). We aimed to identify in hepatocytes the protein NOX complex responsible for H(2)O(2) synthesis after α(1)-adrenoceptor (α(1)-AR) stimulation, its activation mechanism, and to… CONTINUE READING