NOX enzymes as drug targets

  title={NOX enzymes as drug targets},
  author={Karl-Heinz Krause and David J Lambeth and M D Kurt Kroenke},
  booktitle={Cellular and Molecular Life Sciences},
The Nox field (for review see [3, 4] has seen two distinct epochs: (1) the Age of the Phagocyte Oxidase, which began in earnest more than 30 years ago, during which the respiratory burst oxidase was believed to be the sole ‘‘professional’’ generator of reactive oxygen species (ROS), the production of which was thought to be largely confined to phagocytic cells, and (2) the Age of the Nox Family, which began around the turn of the 21st century and which showed the existence of multiple Nox… CONTINUE READING


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