NORA: a simple and reliable parameter for estimating renal output with or without frusemide challenge.

@article{Piepsz2000NORAAS,
  title={NORA: a simple and reliable parameter for estimating renal output with or without frusemide challenge.},
  author={Amy Piepsz and Marianne C Tondeur and Hamphrey R. Ham},
  journal={Nuclear medicine communications},
  year={2000},
  volume={21 4},
  pages={317-23}
}
The aim of this study was to evaluate a simple parameter describing renal output, namely NORA (normalized residual activity). We first compared, in a simulated model, different parameters of transit to an ideal standard; we then compared, in a clinical study, NORA and output efficiency. 123I-hippurate, 99Tcm-DTPA and 99Tcm-MAG3 plasma curves, each with two levels of renal clearance, were convoluted by means of different types of simulated retention functions, with different mean transit times… CONTINUE READING

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