NON-INVASIVE QUANTITATION OF CORNEAL COPPER IN HEPATOLENTICULAR DEGENERATION (WILSON'S DISEASE)

@article{Belkin1976NONINVASIVEQO,
  title={NON-INVASIVE QUANTITATION OF CORNEAL COPPER IN HEPATOLENTICULAR DEGENERATION (WILSON'S DISEASE)},
  author={Michael Belkin and Ran Zeimer and Tova Chajek and Gilberto Friedman and Eldad Melamed},
  journal={The Lancet},
  year={1976},
  volume={307},
  pages={391-392}
}
The corneal copper content was measured by X-ray excitation spectrometry in two controls and in seven patients with Wilson's disease. Patients who were treated irregularly or not treated at all showed a high corneal copper content. Those who were adequately treated had low levels, comparable to the controls. In one case the corneal copper content declined 45%, after a course of dimercaprol. The corneal copper measured showed no correlation with the slit-lamp appearance of the Kayser-Fleischer… CONTINUE READING