NOD1 and NOD2 in inflammation, immunity and disease.

@article{Mukherjee2018NOD1AN,
  title={NOD1 and NOD2 in inflammation, immunity and disease.},
  author={Tapas Mukherjee and Elise Sofie Hovingh and Elisabeth G. Foerster and Mena Abdel-Nour and Dana J. Philpott and Stephen E. Girardin},
  journal={Archives of biochemistry and biophysics},
  year={2018}
}

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Anaplasma phagocytophilum Induces TLR- and MyD88-Dependent Signaling in In Vitro Generated Murine Neutrophils

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Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress

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Application and prospect of targeting innate immune sensors in the treatment of autoimmune diseases

This review emphasizes the roles of different PRRs in activating both innate and adaptive immunity, which can coordinate to trigger autoimmune responses, and may prompt the formulation of novel ideas for developing therapeutic strategies against autoimmune diseases by targeting PRRs-related signals.

Regulation of Immune Homeostasis via Muramyl Peptides-Low Molecular Weight Bioregulators of Bacterial Origin

To create networks, data from numerous biomedical and clinical research databases were used to prepare expert systems for use in pharmacological and biomedical research with an emphasis on muramyl dipeptides, with the aim of understanding intrinsic pathways of homeostasis.
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Recent findings have expanded the scope of the cellular compartments monitored by NOD1 and NOD2 and have elucidated the signalling pathways that are triggered downstream of NOD activation, indicating that a balanced level of N OD signalling is crucial for the maintenance of immune homeostasis.

NOD1 and NOD2 Signaling in Infection and Inflammation

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Signalling pathways and molecular interactions of NOD1 and NOD2

This work focuses on the molecular interactions between these NOD proteins and other intracellular molecules to elucidate the mechanisms by which NOD1 and NOD2 contribute to the maintenance of mucosal homeostasis and the induction of mucosa inflammation.

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A Novel Motif in the Crohn's Disease Susceptibility Protein, NOD2, Allows TRAF4 to Down-regulate Innate Immune Responses*

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The Bacterial Peptidoglycan-Sensing Molecules NOD1 and NOD2 Promote CD8+ Thymocyte Selection

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