NOD-like receptors: versatile cytosolic sentinels.

@article{Motta2015NODlikeRV,
  title={NOD-like receptors: versatile cytosolic sentinels.},
  author={Vin{\'i}cius Motta and Fraser Soares and Tian Sun and Dana J. Philpott},
  journal={Physiological reviews},
  year={2015},
  volume={95 1},
  pages={
          149-78
        }
}
Nucleotide binding oligomerization domain (NOD)-like receptors are cytoplasmic pattern-recognition receptors that together with RIG-I-like receptor (retinoic acid-inducible gene 1), Toll-like receptor (TLR), and C-type lectin families make up the innate pathogen pattern recognition system. There are 22 members of NLRs in humans, 34 in mice, and even a larger number in some invertebrates like sea urchins, which contain more than 200 receptors. Although initially described to respond to… 

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