NOCIt: a computational method to infer the number of contributors to DNA samples analyzed by STR genotyping.

@article{Swaminathan2015NOCItAC,
  title={NOCIt: a computational method to infer the number of contributors to DNA samples analyzed by STR genotyping.},
  author={Harish Swaminathan and Catherine Grgicak and Muriel M{\'e}dard and Desmond S. Lun},
  journal={Forensic science international. Genetics},
  year={2015},
  volume={16},
  pages={172-180}
}
Repetitive sequences in the human genome called short tandem repeats (STRs) are used in human identification for forensic purposes. Interpretation of DNA profiles generated using STRs is often problematic because of uncertainty in the number of contributors to the sample. Existing methods to identify the number of contributors work on the number of peaks observed and/or allele frequencies. We have developed a computational method called NOCIt that calculates the a posteriori probability (APP… CONTINUE READING
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