NO mediates ginsenoside Rg1-induced long-term potentiation in anesthetized rats.

@article{Wang2001NOMG,
  title={NO mediates ginsenoside Rg1-induced long-term potentiation in anesthetized rats.},
  author={Xin-hua Wang and Jietao Tao Zhang},
  journal={Acta pharmacologica Sinica},
  year={2001},
  volume={22 12},
  pages={1099-102}
}
AIM To investigate the effect of ginsenoside Rg1 on synaptic transmission in anesthetized rats and the effect of NOS inhibitor, 7-nitroindazole (7-NI), on long-term potentiation (LTP) induced by Rg1. METHODS Extracellular recording technique was used to record the population spike (PS) in the dentate gyrus (DG) of anesthetized rats. Drug or vehicle injections were delivered via a cannula in the lateral cerebral ventricle. RESULTS Rg1 (10 and 100 nmol/L) enhanced the basic synaptic… CONTINUE READING