NMR structure of Plasmodium falciparum malaria peptide correlates with protective immunity.

@article{Purmova2002NMRSO,
  title={NMR structure of Plasmodium falciparum malaria peptide correlates with protective immunity.},
  author={Jindra Purmova and Luz Mary Salazar and Fabiola Espejo and Mary Helena Torres and Marcia Cubillos and Elizabeth Molina Torres and Yolanda Blanco L{\'o}pez and Ra{\'u}l A. Ponce Rodriguez and Manuel Elkin Patarroyo},
  journal={Biochimica et biophysica acta},
  year={2002},
  volume={1571 1},
  pages={27-33}
}
Apical membrane antigen-1 is an integral Plasmodium falciparum malaria parasite membrane protein. High activity binding peptides (HABPs) to human red blood cells (RBCs) have been identified in this protein. One of them (peptide 4313), for which critical binding residues have already been defined, is conserved and nonimmunogenic. Its critical binding residues were changed for amino acids having similar mass but different charge to change such immunological properties; these changes generated… CONTINUE READING