NMR structure of CXCR3 binding chemokine CXCL11 (ITAC).

@article{Booth2004NMRSO,
  title={NMR structure of CXCR3 binding chemokine CXCL11 (ITAC).},
  author={Valerie Booth and I Clark-lewis and Brian D. Sykes},
  journal={Protein science : a publication of the Protein Society},
  year={2004},
  volume={13 8},
  pages={2022-8}
}
CXCL11 (ITAC) is one of three chemokines known to bind the receptor CXCR3, the two others being CXCL9 (Mig) and CXCL10 (IP-10). CXCL11 differs from the other CXCR3 ligands in both the strength and the particularities of its receptor interactions: It has a higher affinity, is a stronger agonist, and behaves differently when critical N-terminal residues are… CONTINUE READING