NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain

@article{Huang1996NMRSA,
  title={NMR structure and mutagenesis of the Fas (APO-1/CD95) death domain},
  author={Baohua Huang and M. Eberstadt and E. Olejniczak and R. Meadows and S. Fesik},
  journal={Nature},
  year={1996},
  volume={384},
  pages={638-641}
}
PROGRAMMEDcell death (apoptosis) mediated by the cytokine receptor Fas is critical for the removal of autoreactive T cells1, the mechanism of immune privilege2,3, and for maintenance of immune-system homeostasis4. Signalling of programmed cell death involves the self-association of a conserved cytoplasmic region of Fas called the death domain5–7 and interaction with another death-domain-containing protein, FADD8 (also known as MORT1)9. Although death domains are found in several proteins10… Expand
NMR structure and mutagenesis of the FADD (Mort1) death-effector domain
NMR structure of the apoptosis- and inflammation-related NALP1 pyrin domain.
Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1.
Structure and function of Fas/Fas ligand.
The Solution Structure of FADD Death Domain
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