NMR solution structure of the 205-316 C-terminal fragment of thermolysin. An example of dimerization coupled to partial unfolding.

Abstract

The solution structure of the C-terminal fragment 205-316 of thermolysin has been determined by 1H-NMR methods. The fragment forms a dimer in which each subunit has two different regions: the largely disordered N-terminal segment 205-260 and the structurally well-defined segment 261-316. The structured part of each subunit is composed of three helices and… (More)

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@article{ConejeroLara1997NMRSS, title={NMR solution structure of the 205-316 C-terminal fragment of thermolysin. An example of dimerization coupled to partial unfolding.}, author={Francisco Conejero-Lara and C Gonz{\'a}lez and Mar{\'i}a A. Jim{\'e}nez and Savita Padmanabhan and Pedro L. Mateo and Manuel Rico}, journal={Biochemistry}, year={1997}, volume={36 39}, pages={11975-83} }