NMR of hyperpolarized (129)Xe in the canine chest: spectral dynamics during a breath-hold.

@article{Ruppert2000NMROH,
  title={NMR of hyperpolarized (129)Xe in the canine chest: spectral dynamics during a breath-hold.},
  author={Kai Ruppert and James R. Brookeman and Klaus D. Hagspiel and B Driehuys and John P. Mugler},
  journal={NMR in biomedicine},
  year={2000},
  volume={13 4},
  pages={220-8}
}
One of the major goals of hyperpolarized-gas MR imaging has been to obtain (129)Xe dissolved-phase images in humans. Since the dissolved-phase signal is much weaker than the gas-phase signal, highly optimized MR pulse sequences are required to obtain adequate images during a single breath-hold. In particular, a solid understanding of the temporal dynamics of xenon as it passes from the lung gas spaces into the parenchyma, the blood and other downstream compartments is absolutely essential… CONTINUE READING