NMR metabolic and physiological markers of therapeutic response.

  title={NMR metabolic and physiological markers of therapeutic response.},
  author={Seung-Cheol Lee and Harish Poptani and E. James Delikatny and Stephen Pickup and David Spencer Nelson and Stephen J. Schuster and Sunita Dwivedy Nasta and Jakub Svoboda and Steven C. Goldstein and Stephen Gray Wallace and L A Loevner and Eric Albert Mellon and Ravinder Reddy and Jerry David Glickson},
  journal={Advances in experimental medicine and biology},
Identification of reliable metabolic and physiological NMR detectable markers for prediction and early detection of therapeutic response is essential to enabling NMR guided individualized therapy for cancer. Because non-Hodgkin's lymphoma (NHL) is a prevalent form of cancer that exhibits~50% response to therapy and often presents with large superficial lesions easily accessible to multinuclear magnetic resonance spectroscopy (MRS) measurements, it is an ideal test bed for development of NMR… CONTINUE READING