NMR diffusion and relaxation study of drug-protein interaction.


In this work, NMR diffusion and relaxation measurements are applied to the study of the interaction between the anti-inflammatory drug salicylate and the human serum albumin (HSA) in solutions. The self-diffusion coefficients and the spin-lattice relaxation rates of salicylate are measured as a function of the concentration. The dissociation constant, Kd… (More)


Cite this paper

@article{Luo1999NMRDA, title={NMR diffusion and relaxation study of drug-protein interaction.}, author={Ruiming Luo and M. L. Liu and Xiao-lu Mao}, journal={Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy}, year={1999}, volume={55A 9}, pages={1897-901} }