Metabolic differences of two Ferula species as potential sources of galbanum: An NMR-based metabolomics study.
- BiologyPhytochemical analysis : PCA
Clear metabolomics discrimination of F. gummosa and F. galbaniflua makes their chemotaxonomic classification possible, and shows a clear separation between the two species.
Volatile sulfur compounds: The possible metabolite pattern to identify the sources and types of asafoetida by headspace GC/MS analysis
A validated 1H-NMR method for quantitative analysis of DOTAP lipid in nanoliposomes containing soluble Leishmania antigen.
- Chemistry, BiologyJournal of pharmaceutical and biomedical analysis
SHOWING 1-10 OF 44 REFERENCES
Metabolite profiling and fingerprinting of Hypericum species: a comparison of MS and NMR metabolomics
Anti-cancer in vitro assays to evaluate the ability of extracts from Hypericum species in inhibiting prostate and colon cancer growth suggest that such bioactivity might be predicted by gross metabolic profiling.
Comparative metabolite profiling and fingerprinting of medicinal licorice roots using a multiplex approach of GC-MS, LC-MS and 1D NMR techniques.
- Biology, ChemistryPhytochemistry
Gummosin, a sesquiterpene coumarin from Ferula assa-foetida is preferentially cytotoxic to human breast and prostate cancer cell lines
- Biology, ChemistryAvicenna journal of phytomedicine
The preferential cytotoxic activity of gummosin against cancer cell lines is reported for the first time in this study.
Investigation of species and environmental effects on rhubarb roots metabolome using 1H NMR combined with high performance thin layer chromatography
- Biology, ChemistryMetabolomics
The NMR and HPTLC profiles showed that while chemical variations of rhubarb are in some degree affected by all the factors tested in this study, the most influential factor was altitude of growth.
Traditional uses, phytochemistry and pharmacology of asafoetida (Ferula assa-foetida oleo-gum-resin)-a review.
- BiologyJournal of ethnopharmacology
Metabolic Profiling and Classification of Propolis Samples from Southern Brazil: An NMR-Based Platform Coupled with Machine Learning.
- BiologyJournal of natural products
The NMR-based metabolomics analytical platform, coupled to bioinformatic tools, allowed characterization and classification of Brazilian propolis samples regarding the metabolite signature of important compounds, i.e., chemical fingerprint, harvest seasons, and production regions.
Determination and Quantification of Ferulic acid in Ferula asafoetida by a Validated HPTLC Method
The developed HPTLC method was validated for various validation parameters such as linearity, precision, accuracy as recovery, specificity, detection and quantification limits and can be employed as a quality control tool for checking the purity of asafoetida resin powder, commercially available asafeetida and formulations comprising of asfoetIDA.
Antinociceptive effect of Ferula assa-foetida oleo-gum-resin in mice
- BiologyResearch in pharmaceutical sciences
According to the findings, asafoetida exhibited a significant antinociceptive effect on chronic and acute pain in mice, which probably involve central opioid pathways and peripheral anti-inflammatory action.
Rapid screening for the adulterants of Berberis aristata using direct analysis in real-time mass spectrometry and principal component analysis for discrimination
- ChemistryFood additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
The study reports the rapid analytical method to identify the possibility of illegal adulteration/contamination/substitution in potential plant materials and herbal extracts and indicates it is a quick and reliable method for the direct profiling of B. aristata and its adulterant plants and plant parts.
LC-MS- and (1)H NMR-Based Metabolomic Analysis and in Vitro Toxicological Assessment of 43 Aristolochia Species.
- BiologyJournal of natural products
The results undermine the assumption that 1 and 2 are exclusively responsible for the toxicity of Aristolochia species, and other analogues are likely to contribute to their toxicity and need to be considered as nephrotoxic agents.