NMR and CD conformational studies of bradykinin and its agonists and antagonists: application to receptor binding.

  title={NMR and CD conformational studies of bradykinin and its agonists and antagonists: application to receptor binding.},
  author={George Kotovych and John R. Cann and John M Stewart and H Yamamoto},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  volume={76 2-3},
Most physiological processes are regulated by peptides that perform their functions by interacting with specific receptors on cells. Specific conformations of the peptides are required for correct interactions to take place, and a knowledge of the biologically important conformation is vital for the understanding of biological function. Over the last few years extensive studies using nuclear magnetic resonance and circular dichroism have been carried out on bradykinin (Arg1-Pro2-Pro3-Gly4-Phe5… Expand
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