NMDA receptors in nervous system diseases

@article{Zhou2013NMDARI,
  title={NMDA receptors in nervous system diseases},
  author={Qiang Zhou and Morgan Sheng},
  journal={Neuropharmacology},
  year={2013},
  volume={74},
  pages={69-75}
}
NMDA receptor (NMDAR) dysfunction has emerged as a common theme in several major nervous system disorders, including ischemic brain injury, chronic neurodegenerative diseases, pain, depression and schizophrenia. Either hyperactivity or hypofunction of NMDARs could contribute to disease pathophysiology. It is likely that distinct subtypes of NMDARs (as defined by subunit composition and/or subsynaptic location) are differentially involved in central nervous system diseases. Here we focus on a… CONTINUE READING

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