NMDA receptor subunit gating – uncovered

@article{Gibb2004NMDARS,
  title={NMDA receptor subunit gating – uncovered},
  author={Alasdair J Gibb},
  journal={Trends in Neurosciences},
  year={2004},
  volume={27},
  pages={7-10}
}
Kinetically distinct contributions of NMDA receptor NR1 and NR2 subunits to channel gating have recently been inferred by Banke and Traynelis from single-channel recordings of recombinant NR1–NR2B receptors. The results suggest a new mechanism for receptor activation that will enhance our insight into excitatory synaptic transmission in the brain. In the post-genomic era, this represents an exciting advance in understanding the relationship between structure and function for this unique class… CONTINUE READING

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