NMDA receptor pathways as drug targets

  title={NMDA receptor pathways as drug targets},
  author={John A. Kemp and R Mckernan},
  journal={Nature Neuroscience},
  volume={5 Suppl 1},
Since the mid 1980s, there has been a great deal of enthusiasm within both academia and industry about the therapeutic potential of drugs targeting the NMDA subtype of glutamate receptors. That early promise is just beginning to translate into approvable drugs. Here we review the reasons for this slow progress and critically assess the future prospects for… CONTINUE READING