NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia

@inproceedings{Snyder2013NMDAHA,
  title={NMDA hypofunction as a convergence point for progression and symptoms of schizophrenia},
  author={Melissa A. Snyder and Wen-Jun Gao},
  booktitle={Front. Cell. Neurosci.},
  year={2013}
}
Schizophrenia is a disabling mental illness that is now recognized as a neurodevelopmental disorder. It is likely that genetic risk factors interact with environmental perturbations to affect normal brain development and that this altered trajectory results in a combination of positive, negative, and cognitive symptoms. Although the exact pathophysiology of schizophrenia is unknown, the N-methyl-D-aspartate receptor (NMDAR), a major glutamate receptor subtype, has received great attention… CONTINUE READING
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