NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.

@article{Zhang1989NMDAAA,
  title={NMDA antagonists and potentiation of NMDA-induced motoneuron depolarizations in the isolated frog spinal cord.},
  author={De Xing Zhang and John C. Hackman and Robert A. Davidoff},
  journal={Brain research},
  year={1989},
  volume={493 1},
  pages={129-35}
}
The action of N-methyl-D-aspartate (NMDA) antagonists on motoneurons was studied in the isolated, hemisected frog spinal cord using sucrose gap techniques. NMDA-evoked motoneuron depolarizations were depressed by application of APV, APH, kynurenate, Mg2+ ions, ketamine, and MK-801. Upon returning to normal Ringer's solution after exposure to all antagonists… CONTINUE READING