NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by GABAA receptor blockade in the medial hypothalamus.

@article{Freitas2014NMDAAA,
  title={NMDA and AMPA/kainate glutamatergic receptors in the prelimbic medial prefrontal cortex modulate the elaborated defensive behavior and innate fear-induced antinociception elicited by GABAA receptor blockade in the medial hypothalamus.},
  author={Renato Leonardo de Freitas and Carlos Jos{\'e} Salgado-Rohner and Audrey Francisco Biagioni and Priscila Fernandes Viana Medeiros and Jaime Eduardo Cecilio Hallak and Jos{\'e} Alexandre de Souza Crippa and Norberto Cysne Coimbra},
  journal={Cerebral cortex},
  year={2014},
  volume={24 6},
  pages={1518-28}
}
The aim of the present study was to investigate the involvement of N-methyl-d-aspartate (NMDA) and amino-3-hydroxy-5-methyl-isoxazole-4-proprionate (AMPA)/kainate receptors of the prelimbic (PL) division of the medial prefrontal cortex (MPFC) on the panic attack-like reactions evoked by γ-aminobutyric acid-A receptor blockade in the medial hypothalamus (MH). Rats were pretreated with NaCl 0.9%, LY235959 (NMDA receptor antagonist), and NBQX (AMPA/kainate receptor antagonist) in the PL at 3… CONTINUE READING
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The rat brain in sterotaxic coordinates

  • G Paxinos, C. Watson
  • London: Academic Press.
  • 1997
Highly Influential
3 Excerpts

Medial pre-frontal cortex and CB1 endocannabinoid receptors in the antinociception induced by elaborated escape behaviour caused by disinhibition of hypothalamus

  • RL de Freitas, CJ Salgado-Rohner, JEC Hallak, JAS Crippa, NC. Coimbra
  • Eur J Pain
  • 2011
Highly Influential
4 Excerpts

Physiological arousal elicited by sodium lactate infusion in rats with dorsomedial hypothalamic GABA dysfunction

  • A Shekhar, SR Keim, JR Simon, WJ. McBride
  • Pharmacol Biochem Behav. 55:249–256.
  • 1996
Highly Influential
6 Excerpts

Noradrenergic pathways between locus coeruleus and dorsal raphe nucleus mediate analgesia induced by defensive behaviour evoked by lateral hypothalamus

  • CJ Salgado-Rohner, RL de Freitas, NC. Coimbra
  • Eur J Pain
  • 2011

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