NMDA Actions on Rat Abducens Motoneurons.

  title={NMDA Actions on Rat Abducens Motoneurons.},
  author={Jacques Durand},
  journal={The European journal of neuroscience},
  volume={3 7},
Intracellular recordings were made from rat abducens motoneurons in vivo during local extracellular micro-ionophoretic application of N-methyl-d-aspartate (NMDA) and NMDA receptor antagonists. Typical NMDA responses, at a resting potential of -60 mV, consisted of a slow depolarization with an apparent increase in membrane resistance, bursts of action potentials followed by stable repetitive firing. Ionophoretic applications of aminophosphonovalerate (APV), kynurenate or MK801 reduced or blocked… CONTINUE READING

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