NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway

Abstract

The effector functions of natural killer cells are regulated by activating receptors, which recognize stress-inducible ligands expressed on target cells and signal through association with signaling adaptors. Here we developed a mouse model in which a fusion of the signaling adaptor DAP10 and ubiquitin efficiently downregulated expression of the activating… (More)
DOI: 10.1038/ni1524

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@article{Horng2007NKG2DSI, title={NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway}, author={Tiffany Horng and Jelena S. Bezbradica and Ruslan Medzhitov}, journal={Nature Immunology}, year={2007}, volume={8}, pages={1345-1352} }