NK phenotypic markers and IL2 response in NK cells from elderly people.

@article{Borrego1999NKPM,
  title={NK phenotypic markers and IL2 response in NK cells from elderly people.},
  author={Filipa Borrego and M Carmen Alonso and Maria Dolores Galiani and Julia Carracedo and R V Santana Ramirez and Bel{\'e}n Ostos and Jos{\'e} Salvador C{\'a}novas Pe{\~n}a and Rafael Sabido Solana},
  journal={Experimental gerontology},
  year={1999},
  volume={34 2},
  pages={253-65}
}
Immunosenescence is a process that primarily affects the T cell compartment of the immune system, although age-associated immunological alterations have also been demonstrated in the NK cell phenotype and function. A significant expansion in the number of NK cells is found in aging. The NK cytotoxic capacity of total peripheral blood lymphocytes is also well preserved, not only in healthy elderly people but also in centenarians. However, NK cell killing of K562 is impaired when considered in a… CONTINUE READING

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